Preheat oven to 425°. Spread bread cubes in a single layer in a large rimmed baking pan. Bake for 8 minutes or until bread is lightly browned and toasted; cool.

Transfer bread cubes to a large bowl. Add chopped apple, Brussels sprouts, and celery; set aside.

Combine broth, apple juice, butter, minced onion, and poultry seasoning in a mediums saucepan; bring to boiling over medium-high heat. Remove from heat and pour over bread mixture. Cover and let stand 5 minutes. Toss with a fork before serving.